Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development. * Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability * Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development * Explains how preclinical animal models - ...
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Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development. * Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability * Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development * Explains how preclinical animal models - used in preclinical testing - and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development * Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS) * Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development
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Seller's Description:
PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
