This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 edition. Excerpt: ...i.e., are repulsion-leucocytoses. Functional leucocytosis and lymphocytosis due to chemiotaxis are of an active or reactionary character. Generally, however, active functional leucocytosis is associated with some cause leading to metaplasia. An increase in number is the commonest sign of the presence of a ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 edition. Excerpt: ...i.e., are repulsion-leucocytoses. Functional leucocytosis and lymphocytosis due to chemiotaxis are of an active or reactionary character. Generally, however, active functional leucocytosis is associated with some cause leading to metaplasia. An increase in number is the commonest sign of the presence of a simple Ieucocytosis or of a leukaemia. Acute leukaemias due to an infection ought perhaps rather to be classed among the metaplastic leucocytoses than among the actual hyperplastic leukaemias. At the same time, transition forms might exist between toxic metaplasia on the one hand and metahyperplasia on the other, that is to say, hyperplasia combined with toxic metaplasia, whence the name hypermetaplasia. But irritative conditions due to interference with function, as well as leukaemic changes in the bloodforming apparatus, may exist without any increase in the leucocyte count (e.g., the leucopenic type of Ieucocytosis, the aleukaemic or subleukaemic form of leukaemia). Hence it follows that the crucial sign of the presence of one or other of these conditions must be sought for in the qualitative nature of the cell present. In both affections, early types of cell have been found in the blood. The occasional appearance of early forms is thus the essential criterion of a simple or of a leukaemic Ieucocytosis. There is this difference, however, in the simple leucocytoses: early forms may appear In the blood, whereas in leukaemias they are always and of necessity present. Hence it comes about that in leucocytoses, when early forms are present at all, they are generally more or less scarce, and are then only the immediate ontogenetic precursors of the mature polymorphonuclear leucocyte. In the lymphocytoses, the early forms are usually lymphocytes...
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