Manuel Serrano

Dr. Manuel Serrano did his PhD under the supervision of Margarita Salas (CBM-CSIC, Madrid) and a postdoctoral stay in David Beach's lab (Cold Spring Harbor Laboratory, NY, USA) from 1992 to 1996. During this time, he made one of his most important contributions, namely the discovery of the tumor suppressor p16. The main contributions of Dr. Serrano's lab during these years are related to the concept of oncogene-induced senescence and the anti-ageing activity of tumor suppressors. More recently,...See more

Dr. Manuel Serrano did his PhD under the supervision of Margarita Salas (CBM-CSIC, Madrid) and a postdoctoral stay in David Beach's lab (Cold Spring Harbor Laboratory, NY, USA) from 1992 to 1996. During this time, he made one of his most important contributions, namely the discovery of the tumor suppressor p16. The main contributions of Dr. Serrano's lab during these years are related to the concept of oncogene-induced senescence and the anti-ageing activity of tumor suppressors. More recently, his group has reported on the relevance of tumor suppressors in metabolic syndrome, the existence of senescence during embryonic development, and the feasibility of embryonic reprogramming within living adult organisms (the latter was considered "Achievement of the Year 2013" in the stem cells field by Nature Medicine). See less