Lingyan Shi

Lingyan Shi is an Assistant Professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering. She is developing and applying new ultrafast laser scanning optical imaging and spectroscopic technologies, such as stimulated Raman scattering (SRS) microscopy for solving biological questions. Her recent major scientific contributions include the discovery of the "Golden Optical Window? for deep brain imaging, and the development of a breakthrough platform that combines...See more

Lingyan Shi is an Assistant Professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering. She is developing and applying new ultrafast laser scanning optical imaging and spectroscopic technologies, such as stimulated Raman scattering (SRS) microscopy for solving biological questions. Her recent major scientific contributions include the discovery of the "Golden Optical Window? for deep brain imaging, and the development of a breakthrough platform that combines deuterium probing with SRS for optical imaging of metabolic dynamics in living organisms. She is combining bioorthogonal labeling and SRS imaging for directly visualizing complex molecular events in brain, tumor, and metabolic diseases at sub-cellular scale in situ, which offer powerful tools potentially for disease detection, diagnosis and treatment, as well as for mechanistic understanding of scientific fundamentals. Shi is a member of OSA, SPIE, and also a member of New York Academy of Science. See less