Beata Jastrzebska

Dr. Beata Jastrzebska is an Assistant Professor in the Department of Pharmacology, School of Medicine, Case Western Reserve University, Ohio. Her lab focuses on understanding the structure and function of the visual G protein coupled receptor (GPCR), rhodopsin. In particular, she is interested in delineating the rhodopsin supramolecular organization and its implications for binding with the cognate heterotrimeric G protein, transducin. Several mutations identified in the rhodopsin gene leading...See more

Dr. Beata Jastrzebska is an Assistant Professor in the Department of Pharmacology, School of Medicine, Case Western Reserve University, Ohio. Her lab focuses on understanding the structure and function of the visual G protein coupled receptor (GPCR), rhodopsin. In particular, she is interested in delineating the rhodopsin supramolecular organization and its implications for binding with the cognate heterotrimeric G protein, transducin. Several mutations identified in the rhodopsin gene leading to the retinal degeneration in humans, such as retinitis pigmentosa (RP), could affect membrane oligomeric organization of this receptor. Therefore, efforts are directed towards understanding the molecular basis of rhodopsin gene associated retinal degradation in humans using biochemical, biophysical, and structural methods. Dr. Jastrzebska has published her research widely in peer reviewed journals and serials, including Biochemistry, Methods in Molecular Biology, JACS, and Methods in Enzymology. See less