Cardiovascular diseases are the number one cause of death and disability in the United States and most European countries. Real-time chronic blood pressure information of genetically engineered mice can help scientists understand the diseases and to develop new drugs and treatments for the diseases. However, there is no adequate solution for chronic blood pressure monitoring to date due to small laboratory mouse size and their small blood vessel dimension. By merging MEMS technology and low-power CMOS integrated circuits ...
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Cardiovascular diseases are the number one cause of death and disability in the United States and most European countries. Real-time chronic blood pressure information of genetically engineered mice can help scientists understand the diseases and to develop new drugs and treatments for the diseases. However, there is no adequate solution for chronic blood pressure monitoring to date due to small laboratory mouse size and their small blood vessel dimension. By merging MEMS technology and low-power CMOS integrated circuits design through a high level system integration together with a conventional molding-based packaging technique, miniature, light- weight, wireless, batteryless, less-invasive, and implantable blood pressure sensing microsystems have been demonstrated for untethered small laboratory animals real-time monitoring. The microsystems designed for laboratory rats and mice monitoring presented in this book exhibit a weight of 430mg and 130mg, respectively. Untethered laboratory animals implant study demonstrates the microsystem capability of capturing real-time high-fidelity blood pressure information under a wireless and batteryless condition.
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