This book is about how proteins encoded by the larger DNA viruses (such as poxviruses, herpesviruses and adenoviruses) interact with elements of the vertebrate immune system to favor propagation in infected hosts. All mammalian viruses in the wild have adapted to the selection pressure exerted by the various effector arms of the immune apparatus, but the DNA viruses with larger genomes have the luxury of being able to encode and express specific viral proteins whose function is to directly subvert or modulate immune ...
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This book is about how proteins encoded by the larger DNA viruses (such as poxviruses, herpesviruses and adenoviruses) interact with elements of the vertebrate immune system to favor propagation in infected hosts. All mammalian viruses in the wild have adapted to the selection pressure exerted by the various effector arms of the immune apparatus, but the DNA viruses with larger genomes have the luxury of being able to encode and express specific viral proteins whose function is to directly subvert or modulate immune recognition and clearance. Up to date information is provided of how such viral immune regulator proteins have co-evolved with the host proteins that mediate natural and acquired immunity.
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