This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1922 edition. Excerpt: ... Chapter II. The Antineuritic Vitamin (and, or) Vitamin B. We have seen that Eijkman, in his papers published from 1897 to 1906, clearly set forth his discovery that a diet of polished rice produces in fowls a condition of nutritional polyneuritis which appears to be essentially identical with typical ...
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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1922 edition. Excerpt: ... Chapter II. The Antineuritic Vitamin (and, or) Vitamin B. We have seen that Eijkman, in his papers published from 1897 to 1906, clearly set forth his discovery that a diet of polished rice produces in fowls a condition of nutritional polyneuritis which appears to be essentially identical with typical beriberi in man, and that this disease is due to the lack of a substance essential to normal nutrition, which substance exists in the rice polishings (i.e., in the outer layers and embryo of the rice kernel) as well as in other natural foods. After the publication of the first of these papers, Grijns (1901) took up the subject, confirmed Eijkman's earlier work and extended it to show that the antineuritic or protective substance which Eijkman had demonstrated to occur in rice, occurs also in legumes and in this case not wholly in the outer layers of the seed. It is interesting to note that at this time he recorded the further fact that the antineuritic substance seemed to disappear when the seeds (Phaseolus radiatus) were germinated, a circumstance which may have special significance in connection with the simultaneous development of the antiscorbutic property (Chapter III). Failure to isolate the antineuritic substance from rice polishings led Grijns to determine whether the heating of unpolished rice (or of the phaseolus seeds) destroyed the protective power. Of four fowls fed unpolished rice which had been heated at 120 C, two died of polyneuritis after five or six months, while two remained well at the end of eleven months. On polished rice fowls may be expected to develop polyneuritis in about three weeks, while with rice unpolished and unheated there should be entire freedom from the disease. Hence Grijns concluded that heating...
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