Excerpt from The Physiologic Chemistry of Uric Acid Nucleohiston may be extracted from finely divided thymus-glands with water, and precipitated from its aqueous solution with acetic acid, avoiding an excess in which the recently precipitated body is soluble. The moist substance is soluble in dilute acids and alkalies and in dilute neutral salt-solution. It is worthy of note that nucleohiston gives the Millon and xantho proteic reactions, and the biuret-coloration faintly on standing. It contains a little more than 3% of ...
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Excerpt from The Physiologic Chemistry of Uric Acid Nucleohiston may be extracted from finely divided thymus-glands with water, and precipitated from its aqueous solution with acetic acid, avoiding an excess in which the recently precipitated body is soluble. The moist substance is soluble in dilute acids and alkalies and in dilute neutral salt-solution. It is worthy of note that nucleohiston gives the Millon and xantho proteic reactions, and the biuret-coloration faintly on standing. It contains a little more than 3% of phos phorus. Novy has found that subcutaneous injection of gram or more in rabbits causes elevation of tem perature of from 1??? to C., preceded by a short period of subnormal temperature. Nucleohiston, as well as its nucleinic-acid constituent, precipitates diph theria-toxin, but, as Novy states, this undoubtedly is a mechanical effect; the toxin being carried down with the precipitated proteids. However, nucleohiston does have some destructive action on diphtheria-toxin after the mixture has stood for some time in vitro, although separate injections do not protect animals. (novy.) About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at ... This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
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