Sickle cell disease is best known as an inherited hemolytic disorder of defective hemoglobin that distorts red blood cell morphology, function and lifespan. It is less well known as a disease that targets the microvasculature, characterized by increased expression of cell adhesion molecules, enhanced production of reactive oxygen species, abnormal blood cell-endothelial cell interactions in postcapillary venules and altered vasomotor responses in arterioles. These microvascular responses are crucial to the initiation and ...
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Sickle cell disease is best known as an inherited hemolytic disorder of defective hemoglobin that distorts red blood cell morphology, function and lifespan. It is less well known as a disease that targets the microvasculature, characterized by increased expression of cell adhesion molecules, enhanced production of reactive oxygen species, abnormal blood cell-endothelial cell interactions in postcapillary venules and altered vasomotor responses in arterioles. These microvascular responses are crucial to the initiation and progression of vasoocclusive crises, the disease's critical pathophysiological event that leads to pain crises, organ injury and early mortality. This work considers sickle cell disease vascular pathology in terms of the cellular, molecular and biochemical players that participate in the evolution, progression and resolution of vasoocclusive crises. The work provides a comprehensive overview of the complex pathophysiology of sickle cell disease and is an ideal reference source for professionals in the medical and scientific community.
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Add this copy of The Pathophysiology of Sickle Cell Disease Cellular, to cart. $79.15, new condition, Sold by Books2anywhere rated 5.0 out of 5 stars, ships from Fairford, GLOUCESTERSHIRE, UNITED KINGDOM, published 2009 by VDM Verlag.
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Add this copy of The Pathophysiology of Sickle Cell Disease Cellular, to cart. $83.77, new condition, Sold by Paperbackshop International rated 5.0 out of 5 stars, ships from Fairford, GLOS, UNITED KINGDOM, published 2009 by VDM Verlag.
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PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
Add this copy of The Pathophysiology of Sickle Cell Disease to cart. $72.07, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2009 by VDM Verlag.
Add this copy of The Pathophysiology of Sickle Cell Disease Cellular, to cart. $94.70, new condition, Sold by Paperbackshop rated 4.0 out of 5 stars, ships from Bensenville, IL, UNITED STATES, published 2009 by VDM Verlag.
Add this copy of The Pathophysiology of Sickle Cell Disease: Cellular, to cart. $124.36, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2009 by VDM Verlag.
