Excerpt from The Effects of Drugs and Other Agencies Upon the Respiratory Movements IN physiological therapeutics a stimulant is a substance which increases functional activity. Accordingly, a vascular stimulant is one which increases the arterial pressure; or to speak more minutely, a cardiac or an arterial stimulant is one that increases the output of force by the heart or by the vaso-motor system. When, however, the function of respiration is in question, a stimulant, as the word is practically used by most ...
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Excerpt from The Effects of Drugs and Other Agencies Upon the Respiratory Movements IN physiological therapeutics a stimulant is a substance which increases functional activity. Accordingly, a vascular stimulant is one which increases the arterial pressure; or to speak more minutely, a cardiac or an arterial stimulant is one that increases the output of force by the heart or by the vaso-motor system. When, however, the function of respiration is in question, a stimulant, as the word is practically used by most pharmacologists, seems to be simply a substance which increases the rapidity of the respiration, Since in almost all recorded experiments with drugs of the class, the experimentor has simply noted the rate of the respiration. Increased activity of rate does not however necessarily imply increased activity of the function. Thus, a rapid pulse may be a very feeble pulse, and an arterial sedative may increase the rate of the pulse though depressing most thoroughly the functional activity of the circulation. In like manner, it is Shown by our experiments that very rapid breathing may coexist with very little movement of air. It is evident that the proper definition of a respiratory stimulant would be, that it is a substance which increases the amount of air taken in and out of the lungs in a fixed time. Such considerations as these have led us to undertake the following research, which has for its object the determination of the respiratory movement of air as affected by different drugs and different agencies. The mode of research is in itself simple enough. It consists essentially of connecting the trachea of the animal with a tube which, in turn, is connected with two ordinary mercurial valves, the one of which allows the air to enter, the other the air to escape; the mercurial valve of expiration being, in turn, connected with an india-rubber bag or reser voir from which the air is drawn through by means of a suction-pump. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at ... This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
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