Excerpt from The American Journal of Anatomy, 1919, Vol. 25 Another instance of dedifferentiation has recently been pointed out by Kunitomo.2 This writer has published the results Of a careful study Of the tail region in alarge number Of human embryos, representing the period Of greatest development Of the caudal appendage, and also the later period of its gradual reduction. He shows that in very young specimens the spinal cord reaches the extreme tip Of the tail and throughout its length is quite uniform in structure. ...
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Excerpt from The American Journal of Anatomy, 1919, Vol. 25 Another instance of dedifferentiation has recently been pointed out by Kunitomo.2 This writer has published the results Of a careful study Of the tail region in alarge number Of human embryos, representing the period Of greatest development Of the caudal appendage, and also the later period of its gradual reduction. He shows that in very young specimens the spinal cord reaches the extreme tip Of the tail and throughout its length is quite uniform in structure. Somewhat later (11 to 15-mm. Stage) it can be divided at about the level of the thirty-second vertebra into two parts - a cranial or main part, having a wide central canal and thick walls in which can be recognized well-developed mantle and marginal zones, and a caudal slender part, having a narrow canal with walls consisting only Of an ependymal zone. Kunitomo shows that it is this caudal atrophic portion that eventually forms the filum terminale. The main part lying cranial to the thirty-second vertebra undergoes uninterrupted and progressive differentiation, whereas the portion caudal to this undergoes re gressive changes and, with the exception Of the extreme tip, finally becomes converted into a fibrous strand, the tip forming the coccygeal medullary vestige. This, therefore, is another instance in which an absorptive adjustment is brought about by the reversion Of the tissue to an earlier embryonic type with a certain amount of subsequent redifferentiation. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at ... This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
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