The pineal is regarded as an ontogenic and evolutionary point of departure for research on the causes of senescence, suppported by in vivo experimental evidence, such as pineal cross-transplantation. Among the findings reported here, that reinforce the concept of the central clock, is the unique ability of melatonin to keep dangerous hydroxyl radicals under control. In addition, studies on the effect of caloric restriction and nutritional factors are building blocks in the understanding of how and why we age and develop ...
Read More
The pineal is regarded as an ontogenic and evolutionary point of departure for research on the causes of senescence, suppported by in vivo experimental evidence, such as pineal cross-transplantation. Among the findings reported here, that reinforce the concept of the central clock, is the unique ability of melatonin to keep dangerous hydroxyl radicals under control. In addition, studies on the effect of caloric restriction and nutritional factors are building blocks in the understanding of how and why we age and develop cancer, together with other studies such as: the role of ubiquitous zinc and of extra-pineal melatonin; the disruption of biological rhythms; ultra-structure in brain diseases and dementia; the transacting factors as key regulatory proteins that mediate families of stress response genes; the aging antigen; the mother steroid DHEA during aging; the role of protein kinase C; the loss of D2 dopamine receptors during aging; brain amyloid formation; the role of cell cycles and cyclic AMP; the pineal peptides; and the decay of central neuro-endocrine-immune functions during aging.
Read Less
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
Textual graphs & tables. Some light page-edge soil. Minor rubbing. VG. 23x15cm, xv, 588 pp, Series: Annals of the New York Academy of Sciences, Volume 719 / Third Stromboli Conference on Aging & Cance. Contains 44 papers. Includes: R.J. Reiter; et al: "Melatonin as a Free Radical Scavenger: Implications for Aging & Age-Related Diseases"; H. -W. Korf "The Pineal Organ as a Component of the Biological Clock: Phylogenetic & Ontogenetic Considerations"; W. Humbert & P. Pevet "The Decrease of Pineal Melatonin Production with Age: Causes & Consequences"; N. Prosenc & J. Cervós-Navarro "Ultrastructural Morphology of the Aged Pineal"; L.N. Edmunds, Jr. "Clocks, Cell Cycles, Cancer, & Aging: Role of the Adenylate Cyclase-Cyclic AMP-Phosphodiesterase Axis in Signal Transduction Between Circadian Oscillator & Cell Division Cycle"; L. Piantanelli; et al: "Modelling the Link between Aging & Mortality Rate"; G., Huether "Melatonin Synthesis in the Gastrointestinal Tract & the Impact of Nutritional Factors on Circulating Melatonin"; A. Turturro; et al: " Mechanisms of Caloric Restriction Affecting Aging & Disease"; W. Meier-Ruge; et al: "What is Primary & What Secondary for Amyloid Deposition in Alzheimer's Disease? "; N. Vassiljev; et al: "The Pineal Gland & Immunity"; E. Mocchegiani; et al: "The Zinc-Melatonin Interrelationship: A Working Hypothesis"; N. Fabris "Neuroendocrine-Immune Aging: An Integrative View on the Role of Zinc"; Y. Touitou & E. Haus "Aging of the Human Endocrine & Neuroendocrine Time Structure"; P.E. Kloeden; et al: "Artificial Life Extension: The Epigenetic Approach"; T. Giraldi; et al: "Stress, Melatonin & Tumor Progression in Mice"; etc.
