Slowness of movement ("bradykinesia") is the most important deficit in Parkinson's disease (PD). Current clinical rating of bradykinesia in PD does not separate the dimensions of slowness and amplitude reduction. We categorized patterns of movement in PD patients on a biaxial classification of speed and amplitude using an electromagnetic tracking device (Polhemus) seeking to determine whether these categories may differentially contribute to motor impairment and disability. Motor impairment was worst in patients with very ...
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Slowness of movement ("bradykinesia") is the most important deficit in Parkinson's disease (PD). Current clinical rating of bradykinesia in PD does not separate the dimensions of slowness and amplitude reduction. We categorized patterns of movement in PD patients on a biaxial classification of speed and amplitude using an electromagnetic tracking device (Polhemus) seeking to determine whether these categories may differentially contribute to motor impairment and disability. Motor impairment was worst in patients with very impaired amplitude and best in patients with normal amplitude. Categories of speed impairment did not show a similar relationship. The Schwab & England disability scale decreased with higher severity levels of the amplitude category but not of speed. Agreement (unweighted kappa) between clinician and Polhemus-derived speed-amplitude classification were moderate for speed and amplitude classifications. Our observations suggest that amplitude and speed impairments might behave differentially in PD and may deserve consideration in a biaxial classification system.
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Choose your shipping method in Checkout. Costs may vary based on destination.
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PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
