Preface xiii 1 Metallodrugs in Medicine: Present, Past, and Future Prospects 1 Imtiyaz Yousuf and Masrat Bashir 1.1 Introduction 2 1.2 Therapeutic Metallodrugs 6 1.2.1 Anticancer Metallodrugs 6 1.2.1.1 Mechanism of Anticancer Action 7 1.2.2 Antimicrobial and Antiviral Metallodrugs 15 1.2.2.1 Antimicrobial Metallodrugs 15 1.2.2.2 Antiviral Metallodrugs 16 1.2.3 Radiopharmaceuticals and Radiodiagnostic Metallodrugs 17 1.2.4 Anti-Diabetic Metallodrugs 19 1.2.5 Catalytic Metallodrugs 22 1.3 Future Prospects 23 1.4 ...
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Preface xiii 1 Metallodrugs in Medicine: Present, Past, and Future Prospects 1 Imtiyaz Yousuf and Masrat Bashir 1.1 Introduction 2 1.2 Therapeutic Metallodrugs 6 1.2.1 Anticancer Metallodrugs 6 1.2.1.1 Mechanism of Anticancer Action 7 1.2.2 Antimicrobial and Antiviral Metallodrugs 15 1.2.2.1 Antimicrobial Metallodrugs 15 1.2.2.2 Antiviral Metallodrugs 16 1.2.3 Radiopharmaceuticals and Radiodiagnostic Metallodrugs 17 1.2.4 Anti-Diabetic Metallodrugs 19 1.2.5 Catalytic Metallodrugs 22 1.3 Future Prospects 23 1.4 Conclusion 25 References 26 2 Chemotherapeutic Potential of Ruthenium Metal Complexes Incorporating Schiff Bases 41 Manzoor Ahmad Malik, Parveez Gull, Ovas Ahmad Dar, Mohmmad Younus Wani, Md Ikbal Ahmed Talukdar and Athar Adil Hashmi 2.1 Introduction 42 2.2 Schiff Base Complexes of Ruthenium as Anticancer Agents 43 2.3 Conclusion 63 References 64 3 Role of Metallodrugs in Medicinal Inorganic Chemistry 71 Manish Kumar, Gyanendra Kumar, Arun Kant and Dhanraj T. Masram 3.1 Introduction 72 3.2 Platinum Anticancer Drugs 74 3.2.1 Nucleophilic Displacement Reactions in Complexes of Platinum 80 3.2.2 Mode of the Interaction of Cisplatin Species With Nitrogen Donors of DNA Strand 80 3.2.3 Systemic Toxicity of Cisplatin 82 3.3 Copper-Based Anticancer Complexes 82 3.3.1 Copper is Essential for Health and Nutrition 82 3.3.2 Healthcare Applications of Copper 83 3.3.3 Copper and Human Health Disorders 83 3.3.3.1 Wilson's Disease (WD) 84 3.3.3.2 Menkes' Disease 85 3.3.4 Role of Copper Complexes as Potential Therapeutic Agents 85 3.3.4.1 Thiosemicarbazones-Based Complexes 86 3.3.4.2 Quinolones-Based Copper Complexes 88 3.3.4.3 Naphthoquinones 88 3.4 Zinc Anticancer Complexes 89 3.4.1 Biologically Importance of Zinc 90 3.4.2 Schiff Base Chemistry 92 3.4.2.1 Schiff Base and Their Metal Complexes 92 3.4.3 Zinc-Based Complexes 93 3.4.4 Top Food Sources of Zinc 94 3.4.5 Role of Zinc in Human Body 97 3.4.6 Zinc as a Health Benefit 98 3.4.7 Zinc in Alloy and Composites 100 3.4.8 Zinc Supplementation as a Treatment 100 3.4.8.1 Zinc Deficiency 101 3.4.8.2 Zinc Toxicity 102 3.4.8.3 Zinc and Viral Infections 102 3.4.9 Gastrointestinal Effects 103 3.5 Future Prospects of Metallodrugs 103 References 104 4 Ferrocene-Based Metallodrugs 115 Hamza Shoukat, Ataf Ali Altaf and Amin Badshah 4.1 Introduction 115 4.2 Ferrocene-Based Antimalarial Agents 117 4.2.1 Mechanism of Action 118 4.3 Ferrocene-Based Antibacterial and Antifungal Drugs 118 4.3.1 Schiff Base Derived Ferrocene Conjugates as Antibacterial Agents 119 4.3.2 Ferrocenyl Guanidines as Antibacterial and Antifungal Agents 121 4.3.3 Sedaxicene as Antifungal Agents 122 4.4 Ferrocene-Based Anti-Tumor and Anti-Cancerous Drugs 123 4.4.1 Ferricenium Salts as Anti-Tumor Agents 124 4.4.2 Ferrocenylalkylazoles Active Anti-Tumor Drugs 124 4.4.3 Ferrocene Conjugated to Peptides for Lung Cancer 125 4.4.4 Ferrocenylalkyl Nucleobases Potential Anti-Cancerous Drugs 126 4.4.5 Ferrocenyl Sub-Ordinates of Illudin-M 126 4.4.6 Ferrocenyl Derivatives of Retinoids Potential Anti-Tumor Drug 127 4.4.7 Targeting Breast Cancer With Selective Ferrocene-Based Estrogen Receptor Modulators (SERM) 128 4.5 Conclusion 131 4.6 Future of Ferrocene-Based Drugs 131 References 132 5 Recent Advances in Cobalt Derived Complexes as Potential Therapeutic Agents 137 Manzoor Ahmad Malik, Ovas Ahmad Dar and Athar Adil Hashmi 5.1 Introduction 137 5.2 Cobalt Complexes as Potential Therapeutic Agents 138 5.3 Conclusion 153 References 154 6 NO-, CO-, and H2S-Based Metallopharmaceuticals 157 R. C. Maurya and J. M. Mir 6.1 Introduction 158 6.2 Signaling Molecules: Concept of "Gasotransmitter" 160 6.2.1 Therapeutic Applications of NO, CO, and H2S 162 6.2.1.1 Exogenous NO Donating Molecules 163 6.3 NO Donors Incorporated in Polymeric Matrices 167 6.3.1 Metal Nitrosyl Complexes 168 6.3.1.1 Sodium Nitroprusside (SNP) 168 6.4 Dinitrosyl Iron Thiol Complexes (DNICs) 170
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Add this copy of Queen Elizabeth in Drama and Related Studies to cart. $13.36, good condition, Sold by Wonder Book - Member ABAA/ILAB rated 5.0 out of 5 stars, ships from Frederick, MD, UNITED STATES.
Add this copy of Queen Elizabeth in Drama and Related Studies to cart. $19.95, very good condition, Sold by THE OREGON ROOM rated 4.0 out of 5 stars, ships from Phoenix, OR, UNITED STATES, published by George Allen & Company.
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Seller's Description:
Very Good. 1950 UK 1st edition, VG/Good DJ in Mylar, price-clipped dustjacket has 2x3-inch piece missing at top edge that does not interfere with lettering, in Mylar, no markings.
Add this copy of Queen Elizabeth in Drama and Related Studies to cart. $20.00, good condition, Sold by Tiber Books rated 4.0 out of 5 stars, ships from Cockeysville, MD, UNITED STATES, published 1950 by George Allen & Unwin, London.
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8vo, hardcover. Vg condition in good dj. NOT ex-library. Contents bright & clean, binding tight; dj lightly edge-nicked, outline of old price-sticker on cover, upper spine has 1/2-inch rubbed spot. 212 p.
Add this copy of Queen Elizabeth in Drama and Related Studies to cart. $32.13, poor condition, Sold by Anybook rated 5.0 out of 5 stars, ships from Lincoln, UNITED KINGDOM, published 1950 by George Allen & Unwin.
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This is an ex-library book and may have the usual library/used-book markings inside. This book has hardback covers. Book contains pencil markings. In poor condition, suitable as a reading copy. Re-bound by library. Please note the Image in this listing is a stock photo and may not match the covers of the actual item, 450grams, ISBN:
Add this copy of Queen Elizabeth in Drama and Related Studies to cart. $58.78, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1950 by Ayer Co Pub.
