The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism - from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys. Here, the authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential ...
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The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism - from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys. Here, the authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. The authors cover everything from the fundamental principles right up to the latest developments using high throughput methods to analyze the pharmacokinetic properties of active substances. Particular emphasis is placed on the impact of pharmacokinetic parameters on the discovery of new drugs - one of the most challenging tasks in global pharmaceutical research. Thus, this book is aimed at all those dealing professionally with the development and application of pharmaceutical substances. Furthermore, the readily comprehensible style of writing makes it equally suitable for students of pharmacy and related subjects, who feel that pharmacokinetics is covered too briefly in the standard textbooks.
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Add this copy of Pharmacokinetics and Metabolism in Drug Design, Volume to cart. $17.03, like new condition, Sold by ThriftBooks-Reno rated 5.0 out of 5 stars, ships from Reno, NV, UNITED STATES, published 2001 by Wiley-Vch.
Add this copy of Pharmacokinetics and Metabolism in Drug Design, Volume to cart. $20.60, good condition, Sold by Once Upon A Time Books rated 2.0 out of 5 stars, ships from Tontitown, AR, UNITED STATES, published 2001 by Wiley-VCH.
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This is a used book in good condition and may show some signs of use or wear. This is a used book in good condition and may show some signs of use or wear.
Add this copy of Pharmacokinetics and Metabolism in Drug Design, Volume to cart. $51.00, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2001 by Wiley-VCH.
