Provides a framework for designing peptide-based therapeutic agents with improved transport and metabolism properties for optimal in vivo activity. Covers recent advances in molecular biology of transporters as well as what is more classically known about drug metabolism and drug transport of amino acids and peptides. Focuses on intestinal peptide transport, liver peptide transport, peptide delivery to the brain, peptide transport in microorganisms, and approaches to limiting peptide metabolism. Reviews the state of ...
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Provides a framework for designing peptide-based therapeutic agents with improved transport and metabolism properties for optimal in vivo activity. Covers recent advances in molecular biology of transporters as well as what is more classically known about drug metabolism and drug transport of amino acids and peptides. Focuses on intestinal peptide transport, liver peptide transport, peptide delivery to the brain, peptide transport in microorganisms, and approaches to limiting peptide metabolism. Reviews the state of knowledge in the field and provides examples of how knowledge of peptide transport was used to design strategies for improved delivery of specific classes of agents. Details experimental systems that can be used to evaluate transport and metabolism of peptide-based drugs.
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Seller's Description:
Good. Good condition. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains. Bundled media such as CDs, DVDs, floppy disks or access codes may not be included.
