This book presents the current knowledge in four related areas presently under active scientific investigation: the physiology of normal synovial joints and osteoarthritis, the most prevalent form of joint disease; the biochemical processes involved in initiating and promoting inflammation; the laboratory models used to identify and characterize new nonsteroidal anti-inflammatory drugs (NSAID); and the medicinal chemistry, pharmacology, metabolic, and clinical aspects of the acidic NSAID administered to humans.
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This book presents the current knowledge in four related areas presently under active scientific investigation: the physiology of normal synovial joints and osteoarthritis, the most prevalent form of joint disease; the biochemical processes involved in initiating and promoting inflammation; the laboratory models used to identify and characterize new nonsteroidal anti-inflammatory drugs (NSAID); and the medicinal chemistry, pharmacology, metabolic, and clinical aspects of the acidic NSAID administered to humans.
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