This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring's well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors ...
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This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring's well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease. The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional mitochondria. Finally, it draws on assisted reproductive technologies to discuss how some of these approaches might be adapted to prevent the transmission of mutant and deleted mtDNA from one generation to the next.
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Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $114.73, new condition, Sold by Ria Christie Books rated 5.0 out of 5 stars, ships from Uxbridge, MIDDLESEX, UNITED KINGDOM, published 2014 by Humana.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $116.45, new condition, Sold by Books2anywhere rated 5.0 out of 5 stars, ships from Fairford, GLOUCESTERSHIRE, UNITED KINGDOM, published 2014 by Humana Press Inc.
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PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $121.72, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2014 by Humana.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $123.73, new condition, Sold by Paperbackshop International rated 2.0 out of 5 stars, ships from Fairford, GLOS, UNITED KINGDOM, published 2014 by Humana Press Inc.
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PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $133.07, new condition, Sold by Booksplease rated 4.0 out of 5 stars, ships from Southport, MERSEYSIDE, UNITED KINGDOM, published 2014 by Humana.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $134.68, new condition, Sold by Paperbackshop rated 4.0 out of 5 stars, ships from Bensenville, IL, UNITED STATES, published 2014 by Humana Press Inc.
Add this copy of Mitochondrial Dna, Mitochondria, Disease and Stem Cells to cart. $139.00, new condition, Sold by Kennys.ie rated 4.0 out of 5 stars, ships from Galway, IRELAND, published 2014 by Humana.
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New. This book shows how the mitochondrial genome is transmitted, segregated and inherited. Opens by describing mtDNA mutations and deletions and showing how these impact the offspring's well-being, covers mtDNA transmission and discusses transmittal and adaptation. Editor(s): John, Justin C. Series: Stem Cell Biology and Regenerative Medicine. Num Pages: 200 pages, 5 black & white tables, biography. BIC Classification: MBGR; PSAK; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 11. Weight in Grams: 314. 2014. 2013th Edition. Paperback.....We ship daily from our Bookshop.
Add this copy of Mitochondrial DNA, Mitochondria, Disease and Stem Cells to cart. $168.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2012 by Humana Press Inc..
