A concise assessment of the risks to human health posed by exposure to limonene, a chemical released to the atmosphere in large amounts from certain trees and bushes as well as from anthropogenic sources. In industry, limonene is used as a solvent in degreasing metals prior to industrial painting, for cleaning in the electronic and printing industries, and as a solvent in paint. The compound is also used as a flavor and fragrance additive in food, household cleaning products, and perfumes. The document is part of a new ...
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A concise assessment of the risks to human health posed by exposure to limonene, a chemical released to the atmosphere in large amounts from certain trees and bushes as well as from anthropogenic sources. In industry, limonene is used as a solvent in degreasing metals prior to industrial painting, for cleaning in the electronic and printing industries, and as a solvent in paint. The compound is also used as a flavor and fragrance additive in food, household cleaning products, and perfumes. The document is part of a new series of brief reports aimed at the characterization of hazards and dose-response for exposures to selected industrial chemicals. With this goal in mind, documents focus on studies and findings considered critical for risk characterization. In experimental animals exposed to limonene, the liver is the principal target organ; exposure affects the amount and activity of different liver enzymes, liver weight, cholesterol levels, and bile flow. Studies indicate that limonene is not genotoxic and has no teratogenic or embryotoxic potential. No case reports or epidemiological studies were available for the evaluation of health effects in humans. For the general population, food is identified the principal source of exposure. The report established a guidance value for the ingestion of limonene of 0.1 mg/kg body weight per day. The report further concluded that, at current estimated levels of intake, limonene in food does not represent a significant risk to human health.
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Add this copy of Limonene (Concise International Chemical Assessment to cart. $53.52, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1998 by World Health Organization.
