This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1893 Excerpt: ...and thus facilitate somewhat the method of determining morphine. Recrystallized from alcohol it crystallizes in groups of fine yellow needles arranged most peculiarly in the shape of warts, which grow one along-side cf the other, and hang from the surface of the liquid looking much like plaits of hair. The salt melts, ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1893 Excerpt: ...and thus facilitate somewhat the method of determining morphine. Recrystallized from alcohol it crystallizes in groups of fine yellow needles arranged most peculiarly in the shape of warts, which grow one along-side cf the other, and hang from the surface of the liquid looking much like plaits of hair. The salt melts, or, better, decomposes, without detonation at 157 C. It differs from the corresponding salt of strychnine, however, in not being insoluble in either water or alcohol, as determinations of its solubility gave the following results: --In distilled water at 13 C.--15-G975 grams of a saturated solution yielded 0-031 grams of morphine picrate (dried at 100) which gives a solubility of 1 part in 500 parts of water. In absolute alcohol at 13 C.--7'2422 grams of a saturated solution yielded 0'009 grams of morphine picrate (dried at 100) which gives a solubility of 1 part in 800 parts of alcohol. This being the case, it is, of course, impossible to make use of the salt as a means of determining morphine. (Alfred Dohme, Ph.D., Laboratory of Prof. Fliickiger, University of Slrassburg, February 17, 1891; Am. Jour. Pharm., April, 1891.) The Chemistry of Opium. At the instigation of my esteemed instructor, Prof. Fliickiger, 1 undertook to study the phenomena which present themselves when opium is dialyzed.-When the investigation was first begun, the prime object in view was to determine, if possible, to what cause the acid reaction of aqueous extract of opium was due, and how morphine was combined in the drug. As the work progressed, it was decided to study the relative quantities of the chief constituents of the drug, and, if possible, then draw conclusions in regard to how these are combined in nature in the same. In how far this has proven successful the ..
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