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Group Sequential Methods with Applications to Clinical Trials

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Group Sequential Methods with Applications to Clinical Trials - Jennison, Christopher, and Turnbull, Bruce W
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This book describes group sequential stopping rules designed to reduce average study length and control Type I and Type II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Group Sequential Methods with ...

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Group Sequential Methods with Applications to Clinical Trials 1999, CRC Press, Oxford

ISBN-13: 9780849303166

Hardcover