This comprehensive book is based on a series of excellent articles, written by experts, that review, analyze and discuss a variety of compelling lines of evidence which point to the idea that the inhibitory capacity of the central nervous system, represented by GABA-mediated neurotransmission, is altered in certain convulsive disorders. Each chapter begins with specialized, topical reviews to lay the foundation for the ensuing material. Topics include the role of GABA in CNS function; clinical aspects of the epilepsies, ...
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This comprehensive book is based on a series of excellent articles, written by experts, that review, analyze and discuss a variety of compelling lines of evidence which point to the idea that the inhibitory capacity of the central nervous system, represented by GABA-mediated neurotransmission, is altered in certain convulsive disorders. Each chapter begins with specialized, topical reviews to lay the foundation for the ensuing material. Topics include the role of GABA in CNS function; clinical aspects of the epilepsies, involvement of GABA in models of epilepsy; the rationale for the use of GABA-mimetics as anticonvulsants; future anticonvulsant therapy and much more.
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