Crystals of macromolecules have become keystones of molecular biology, bridging recombinant DNA and X-ray diffraction analysis. Protein, nucleic acid, and virus crystal growth are now possible, raising hopes that virtually all macromolecules might be studied in this way. This extensively illustrated book, provides a biochemical context in which crystal growth can be pursued and instructs readers in practical aspects of the technology, laying out effective strategies for success. The underlying physical and chemical ...
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Crystals of macromolecules have become keystones of molecular biology, bridging recombinant DNA and X-ray diffraction analysis. Protein, nucleic acid, and virus crystal growth are now possible, raising hopes that virtually all macromolecules might be studied in this way. This extensively illustrated book, provides a biochemical context in which crystal growth can be pursued and instructs readers in practical aspects of the technology, laying out effective strategies for success. The underlying physical and chemical principles are presented in approachable form and the most recent advances are described, those that have succeeded in transforming the growth of macromolecular crystals from a black art to a firmly founded science.
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Seller's Description:
Good; Softcover; 1999, Cold Spring Harbor Laboratory Press; Light wear to covers; Wrinking to top half of first 30 pages due to previous moisture exposure (no stuck pages or staining, and pages otherwise clean and readable); Remainder of pages unmarked; Good binding with moderate lean to spine; Tan covers with crystal illustration & title in black lettering; 586 pages; "Crystallization of Biological Macromolecules (Trends in cell biology), " by Alexander McPherson.