This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1895 Excerpt: ...precipitate the globulin and albumin together by boiling the faintly acidulated urine, and estimate the nitrogen in the washed precipitate by the author's modification of Kjeldahl's method (page 128). In another portion of the urine the globulin is precipitated by saturating the liquid with magnesium sulphate, the ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1895 Excerpt: ...precipitate the globulin and albumin together by boiling the faintly acidulated urine, and estimate the nitrogen in the washed precipitate by the author's modification of Kjeldahl's method (page 128). In another portion of the urine the globulin is precipitated by saturating the liquid with magnesium sulphate, the precipitate collected and washed with magnesium sulphate solution, and the contained nitrogen estimated by the modified Kjeldahl's process. The difference between the two results is the nitrogen corresponding to the albumin of the urine. According to Senator, paraglobulin occurs in urine in cases of lardaceous disease of the kidneys, and has also been found in excess in the intense hypersemia A S resulting from poisoning by cantharides, and in functional albuminuria associated with marked disturbance of the digestive organs. The greater the proportion of paraglobulin present, the more unfavourable appears the diagnosis in Bright's disease. When blood is present in urine, as in nephritis after scarlet fever, there is a large increase in the proportion of paraglobulin. Noel Paton (Brit. Med. Jour., ii., 1890, page 196) finds the ratio of globulin to albumin to vary enormously (from 1: 0'6 to 1: 39). It varies much during the day, and in such an erratic manner that no conclusions can be drawn. Albumoses or Proteoses. Of late years a series of bodies, intermediate in characters and composition between the albumins and peptones, have been isolated, and some of these have been proved to exist in certain forms of pathological urine. Thus G e r r a r d has recently shown (Pharm. Jour., 3, xxiii. 261) that in the milk-treatment of albuminuria no albumin coagulable by heat exists in the urine, but that nitric acid gives a precipitate soluble in excess, or o...
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