Despite significant advances in cancer treatment and measures of neoplastic progression, drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic markers), and markers that measure cancer-associated morbidity is considerable, and overall prognosis as well as predict responses to specific therapy. cancer survival has remained relatively flat over the past All these biomarkers have the potential to greatly augment several decades (1,2). However, new technology the development of successful ...
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Despite significant advances in cancer treatment and measures of neoplastic progression, drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic markers), and markers that measure cancer-associated morbidity is considerable, and overall prognosis as well as predict responses to specific therapy. cancer survival has remained relatively flat over the past All these biomarkers have the potential to greatly augment several decades (1,2). However, new technology the development of successful chemoprevention therapies, allowing exploration of signal transduction pathways, but two specific types of biomarkers will have the most identification of cancer-associated genes, and imaging of immediate impact on successful chemopreventive drug tissue architecture and molecular and cellular function is development--those that measure the risk of developing increasing our understanding of carcinogenesis and cancer invasive life-threatening disease, and those whose mo- progression. This knowledge is moving the focus of cancer lation can "reasonably predict" clinical benefit and, therapeutics, including cancer preventive treatments, to therefore, serve as surrogate endpoints for later-occurring drugs that take advantage of cellular control mechanisms clinical disease. Thus far, the biomarker that best measures to selectively suppress cancer progression. these two phenomena is intraepithelial neoplasia (IEN) Carcinogenesis is now visualized as a multifocal, because it is a near obligate precursor to cancer.
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Add this copy of Cancer Chemoprevention, Volume 2: Strategies for Cancer to cart. $31.99, very good condition, Sold by Book Bear rated 5.0 out of 5 stars, ships from West Brookfield, MA, UNITED STATES, published 2005 by Humana.
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Very Good. Published Without Dust Jacket. 4to-over 9¾"-12" tall. pp. 564. 543 pp. Tightly bound. Corners not bumped. Light bump at head of spine with the word "USED" neatly stamped on the top fore-edge. Text is free of markings. No ownership markings. Published without dust jacket. NOTE: Includes CD-ROM.
Add this copy of Cancer Chemoprevention Volume 2 to cart. $202.63, poor condition, Sold by Books International rated 4.0 out of 5 stars, ships from Toronto, ON, CANADA, published 2005 by Humana.