Summarizes the recent advances in the knowledge of the structure and physiological functions of calcium-binding proteins in the central nervous system, describes their cellular distribution, and discusses their possible association with neurodegenerative disorders and their use as diagnostic tools. Over 200 such proteins have been identified so far, characterized by a common structural motif, the EF-hand; they may someday become important therapeutic targets for preventing neuronal death in human neurodegenerative disorders ...
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Summarizes the recent advances in the knowledge of the structure and physiological functions of calcium-binding proteins in the central nervous system, describes their cellular distribution, and discusses their possible association with neurodegenerative disorders and their use as diagnostic tools. Over 200 such proteins have been identified so far, characterized by a common structural motif, the EF-hand; they may someday become important therapeutic targets for preventing neuronal death in human neurodegenerative disorders. For advanced researchers and clinicians. Annotation copyright Book News, Inc. Portland, Or.
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