The book provides a state-of-the-art look at the biological bases of severe mental illness from the perspective of the researchers making these exceptional discoveries. In 17 chapters, some of the best investigators in the field furnish overviews of their ground-breaking findings and set course for future research efforts.
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The book provides a state-of-the-art look at the biological bases of severe mental illness from the perspective of the researchers making these exceptional discoveries. In 17 chapters, some of the best investigators in the field furnish overviews of their ground-breaking findings and set course for future research efforts.
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Publisher:
American Psychiatric Association Publishing
Published:
1996
Language:
English
Alibris ID:
15791384961
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Seller's Description:
New. 0880487461. *** FREE UPGRADE to Courier/Priority Shipping Upon Request ***-*** IN STOCK AND IMMEDIATELY AVAILABLE FOR SHIPMENT-xvii+[1]+535+[7]pp., SIZE: 23.5 x 15.6 x 3cm--FLAWLESS COPY, PRISTINE, NEVER OPENED--DESCRIPTION: Proceedings of the 73rd Meeting of the Association for Research in Nervous and Mental Disease, December 1993, New York City. Research on the biological basis of psychiatric illness. 42 contributors, 33 U. S. --"The 17 papers survey the recent major advances in understanding the biochemistry, molecular genetics, neuroscience, and brain circuit anatomy as they relate to mental disorders; and such treatment issues as the mechanisms of anti-depressants and atypical anti-psychotic drugs. The topics include cerebral cortical alterations in patients with schizophrenia, linkage and molecular genetics in infantile autism, and postmortem studies of suicide victims. For professionals and students in mental health."-Book News--TABLE OF CONTENTS: -Contributors *--PUBLISHER NOTE: Biology of Schizophrenia and Affective Disease provides a state-of-the-art look at the biological bases of severe mental illness from the perspective of the researchers making these exceptional discoveries. In 17 chapters, some of the best investigators in the field furnish overviews of their ground-breaking findings and set course for future research efforts. From the biology of stress to excitotoxicity in the development of corticolimbic alterations in the schizophrenic brain, this outstanding reference tool explores the explosive progress in the fields of biochemistry, molecular genetics, neuroscience, and brain circuit anatomy and the resultant advances in nearly every aspect of the biology of the brain and mental illness. Cerebral cortical alterations in patients with schizophrenia, linkage and molecular genetics in infantile autism, and postmortem studies of suicide victims and schizophrenic patients are among the topics covered. The book also discusses treatment issues, including the mechanisms of action of antidepressants and atypical antipsychotic drugs. Preface * 1 Introduction to the 73rd Meeting of the Association for Research in Nervous and Mental Disease 1 * 2 The Biology of Stress: From Periphery to Brain 15 * 3 Norepinephrine and Serotonin Transporters: Progress on Molecular Targets of Antidepressants 49 * 4 Excitotoxicity in the Development of Corticolimbic Alterations in Schizophrenic Brain 83 * 5 Dissolution of Cerebral Cortical Mechanisms in Subjects With Schizophrenia 113 * 6 Linkage and Molecular Genetics of Infantile Autism 129 * 7 Epidemiology and Behavioral Genetics of Schizophrenia 163 * 8 Postmortem Studies of Suicide Victims 197 * 9 Schizophrenia: Postmortem Studies 223 * 10 Brain Circuits and Brain Function: Implications for Psychiatric Diseases 239 * 11 Peptides and Affective Disorders 259 * 12 Mechanism of Action of Antidepressants: Monoamine Hypotheses and Beyond 295 * 13 Dopamine and Schizophrenia Revisited 369 * 14 Pathophysiology of Schizophrenia: Insights From Neuroimaging 393 * 15 Abnormal Frontotemporal Interactions in Patients With Schizophrenia 16 Mechanism of Action of Atypical Antipsychotic Drugs: An Update 451 * 17 Overview and Discussion 493 * Index 505. --with a bonus offer--
