This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1908 Excerpt: ...elements, to meet a demand for increased functional activity. In other words, hypertrophy must be looked upon as a physiological process or reaction, whereby the tissue adapts itself to meet the increased requirements produced, it may be, by certain unphysiological, i.e. abnormal, conditions. The condition of ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1908 Excerpt: ...elements, to meet a demand for increased functional activity. In other words, hypertrophy must be looked upon as a physiological process or reaction, whereby the tissue adapts itself to meet the increased requirements produced, it may be, by certain unphysiological, i.e. abnormal, conditions. The condition of hyperplasia is frequently seen in repair, in cases where the reparative processes have been carried out in excess of the actual requirements. Thus, in the repair of a fractured bone, the scaffolding of imperfectly formed osseous tissue or callus, which acts as a temporary means of union and support, may be formed in considerable excess; and if this tissue persists, instead of undergoing absorption as it should normally do, the condition may be regarded as one of hyperplasia. Similarly, such hyperplastic phenomena may be seen in the repair of connective tissue, squamous and other forms of epithelium, etc. In the consideration of the subject of hypertrophy, we must 230 exclude all developmental aberrations in the mere size of organs and tissues, e.g. inequality in the relative size of certain of the paired organs. It must be borne in mind, however, that during foetal as well as in extra-uterine life, true hypertrophy may occur in certain organs when such is necessitated by increased functional demand. All forms of new growth or neoplasm must be carefully differentiated from hypertrophy, and such conditions as abnormal enlargements, say of bone, due to defective absorption; and also any thickening of the tissues due to diseases such as syphilis, chronic tuberculosis, osteitis deformans, acromegaly, myxoedema, etc., none of these conditions being really hypertrophies in the strict sense of our definition. Similarly, we cannot regard as true hypertrophy the...
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