This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1906 Excerpt: ...necrotic center; d, seminiferous tubule (Cameron, in " International Text-book of Surgery"). entities, there are many who believe with Metschnikoff that they are enormous phagocytes. Hektoenf believes that they are active bodies from which cells split off. Giant-cells are not always formed in tubercles, as the ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1906 Excerpt: ...necrotic center; d, seminiferous tubule (Cameron, in " International Text-book of Surgery"). entities, there are many who believe with Metschnikoff that they are enormous phagocytes. Hektoenf believes that they are active bodies from which cells split off. Giant-cells are not always formed in tubercles, as the "International Medical Magazine," vol. 1, No. 10, 1892; vol m No. 2, 1894. t "Journal of Experimental Medicine," vol. in, 1898, p. 21. necrotic changes are sometimes so rapid and widespread as to convert the whole into a mass of unrecognizable fragments. Tubercles are constantly avascular, --t. e., in them no new capillary blood-vessels form, as in other inflammatory tissues, and the coagulation-necrosis soon destroys preexisting capillaries; the avaseularity may be a factor in the necVosis of the larger tuberculous masses, though probablv playing no important part in the degeneration of the small tubercles, which is purely toxic. The minute primitive tubercle was first called a miliary tubercle, and small aggregations of these "crude tubercles" by Laennec. Tubercles may be developed in any tissue and in any organ. In whatever situation they occur, the component cells are either pushed aside or included in the lesion. In miliary tuberculosis of the kidney it is not unusual to find a tubercle including a glomerule, and resolving its component thrombosed capillaries and epithelium into necrotic fragments. In this way the tissues become disorganized and disintegrated. As almost all tissues contain a supporting connectivetissue framework, its fibers must be embodied in the new growth. These possess little vitality, but are more resistant than the cells, and, after the cells of a tubercle have been destroyed, may be d...
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