Interest in the role of N-nitroso compounds in human cancer has magnified due to the widespread use of these compounds in all branches of carcinogenesis research. Here, a knowledge of the chemistry of N-nitrosation is necessary in order to understand the association between N-nitrosamines and human disease. This book opens with a discussion of the problems associated with the analysis of volatile N-nitrosamines, of the various groups of non-volatile N-nitroso compounds and of the apparent total N-nitroso compounds. This is ...
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Interest in the role of N-nitroso compounds in human cancer has magnified due to the widespread use of these compounds in all branches of carcinogenesis research. Here, a knowledge of the chemistry of N-nitrosation is necessary in order to understand the association between N-nitrosamines and human disease. This book opens with a discussion of the problems associated with the analysis of volatile N-nitrosamines, of the various groups of non-volatile N-nitroso compounds and of the apparent total N-nitroso compounds. This is followed by chapters on the chemistry of N-nitroso compounds and of N-nitrosation, on the mechanisms of the endogenous formation of N-nitroso compounds and on the occurrence of N-nitroso-amines and their precursors in the human environment. The next chapter reviews the toxico- logy of N-nitroso compounds in animals or in vitro assay systems considering acute and chronic toxicity, carcinogenicity and teratogenicity of N-nitroso-peptides and N-nitroso bile acids. The penultimate chapter deals with the evidence implicating N- nitroso compounds in human cancer, particularly of the stomach and urinary bladder but also of other sites. The final chapter is concerned with prospects for the future, particularly of N- nitroso compounds and human cancer.
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169 pp., Hardcover, ex library, else text clean and binding tight. -If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.
