Strains of Salmonella Paratyphi A isolated from the patients admitted to the diarrhoea treatment center of ICDDR, B were characterized both at the phenotypic and genotypic levels. Antibiotic susceptibility test revealed that 61% of the strains (n = 19) were sensitive to all the antibiotics used for empirical treatment of paratyphoid fever and 32% strains (n = 10) were resistant only to nalidixic acid. Most of the strains that showed reduced susceptibility to ciprofloxacin, having elevated MIC value (0.5???g/ml). A point ...
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Strains of Salmonella Paratyphi A isolated from the patients admitted to the diarrhoea treatment center of ICDDR, B were characterized both at the phenotypic and genotypic levels. Antibiotic susceptibility test revealed that 61% of the strains (n = 19) were sensitive to all the antibiotics used for empirical treatment of paratyphoid fever and 32% strains (n = 10) were resistant only to nalidixic acid. Most of the strains that showed reduced susceptibility to ciprofloxacin, having elevated MIC value (0.5???g/ml). A point mutation in the gyrA gene was observed at codon 83 (TCC to TTC), which substitutes phenylalanine for. This clearly indicates that a significant number of the S. Paratyphi A strains with reduced susceptibility to ciprofloxacin has been evolved. Of 31 strains, 16 (52%) of S. Paratyphi A strains harbored 35 MDa middle-ranged and non-conjugative plasmid. Pulse-field gel electrophoresis (PFGE) revealed that most of the strains (83%) were clonal regardless of antimicrobial sensitivity patterns.
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Add this copy of Molecular Characterization of Salmonella Paratyphi a to cart. $101.69, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2010 by VDM Verlag Dr. Müller.
